张学尧 教授,博士生导师
教育和工作经历:
2000年-2004年 大学生命科学学院 本科学习
2004年-2009年 大学生物技术研究所 硕博连读
2009年-至今 学应用生物学研究所
研究方向:
1. 昆虫蜕皮激素的合成、运输与调控机制;
2. 昆虫解毒酶对农药的代谢解毒机制。
欢迎报考:
1. 硕士招生范围:071002 动物学(学术学位)、071009 细胞生物学(学术学位)和086000 生物与医药(专业学位)
2. 博士招生范围:071002 动物学
科研项目:
1. 山西省优秀青年基金项目,201901D211194,飞蝗AhR/ARNT信号通路调控谷胱甘肽S-转移酶基因的分子机制研究,2019/09-2022/09,15万元,主持
2. 国家自然科学基金面上项目,31872010,飞蝗CncC/Keap1信号通路调控细胞色素P450基因的分子机制研究,2019/01-2022/12,59万元,主持
3. 山西省自然科学基金,201601D011073,飞蝗细胞色素P450酶对农药的响应及解毒机制研究,2016/01-2018/12,4万元,主持
4. 国家自然科学基金青年项目,31101463,飞蝗谷胱甘肽S-转移酶对马拉硫磷的代谢解毒机制研究,2012/01-2014/12,23万元,主持
5. 教育部博士点基金(新教师类),20111401120009,飞蝗谷胱甘肽S-转移酶对马拉硫磷代谢解毒机制研究,2012/01-2014/12,4万元,主持
6. 山西省青年科技研究基金,2012021027-1,东亚飞蝗谷胱甘肽S-转移酶对西维因的代谢解毒机制研究,2012/01-2014/12,3万元,主持
科技奖励:
1. 张建珍、刘晓健、张建琴、张学尧、秦国华、马恩波 重要农业害虫分子毒理学与几丁质代谢研究,山西省科学技术二等奖,2017.11
代表性论文:
1. Zhang XY*, He QH*, Zhang TT*, Wu HH, Zhang JZ, Ma EB. Characteristics of Halloween genes and RNA interference-mediated functional analysis of LmCYP307a2 in Locusta migratoria. Insect Science, 29: 51-64 (2022).
2. Zhang XY*, Dong J*, Wu HH, Zhang HH, Zhang JZ, Ma EB. Knockdown of cytochrome P450 CYP6 family genes increases susceptibility to carbamates and pyrethroids in the migratory locust, Locusta migratoria. Chemosphere, 223: 48-57 (2019).
3. Zhang XY*, Dong J*, Liu J*, Zhang JQ, Zhang TT, Zhang JZ and Ma EB, Aryl hydrocarbon receptor regulates the expression of LmGSTd7 and is associated with chlorpyrifos susceptibility in Locusta migratoria. Pest Management Science 75: 2916-2924 (2019).
4. Zhang XY, Kang X, Wu H, Silver K, Zhang J, Ma E and Zhu KY, Transcriptome-wide survey, gene expression profiling and exogenous chemical-induced transcriptional responses of cytochrome P450 superfamily genes in migratory locust (Locusta migratoria). Insect Biochemistry & Molecular Biology 100: 66-77 (2018).
5. Zhang XY, Wang JX, Liu J, Li YH, Liu XJ, Wu HH, Ma EB and Zhang JZ, Knockdown of NADPH-cytochrome P450 reductase increases the susceptibility to carbaryl in the migratory locust, Locusta migratoria. Chemosphere 188: 517-524 (2017).
6. Zhang XY, Li YH, Wang JX, Zhang TT, Li T, Dong W, Ma EB and Zhang JZ, Identification and characteristic analysis of the catalase gene from Locusta migratoria. Pesticide Biochem Physiol 132: 125-131 (2016).
7. Yu ZT*, Zhang XY*, Wang YW, Moussian B, Zhu KY, Li S, Ma EB and Zhang JZ, LmCYP4G102: An oenocyte-specific cytochrome P450 gene required for cuticular waterproofing in the migratory locust, Locusta migratoria. Scientific Reports 6: 29980 (2016).
8. Zhang XY, Wang JX, Zhang M, Qin GH, Li DQ, Zhu KY, Ma EB and Zhang JZ, Molecular cloning, characterization and positively selected sites of the glutathione S-transferase family from Locusta migratoria. PLoS ONE 9: e114776 (2014).
联系方式:
E-mail: zxy@sxu.edu.cn
微信号:zxylocusta
电话: 139-3515-1881