副教授

副教授

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张婷婷
时间:2018-07-24 阅读次数:
  
张婷婷,1986年10月生,山西寿阳人,博士,山西大学应用生物学研究所,副教授,硕士研究生导师。

 

教育和工作经历

2005/09-2008/07,西北农林科技大学,生物工程专业,本科,学士。

2008/09-2013/12,西北农林科技大学,遗传学专业硕博连读,博士。

2016/01-2018/01,中国科学院上海植物生理生态研究所博士后

2013/12-至今,山西大学应用生物学研究所,讲师,副教授

 

主要研究方向

昆虫胚胎几丁质发育与进化;

昆虫基因编辑;

巴西苏木素抑制膀胱癌机理研究。

 

科研项目

1.飞蝗几丁质酶5两个亚型的基因编辑及功能研究,国家自然科学基金青年基金,2016.01-2018.12,20万元,31501905,在研。

2.苏复宁洗液抑制膀胱癌分子靶标及信号通路的研究与应用,山西省人才专项(优秀人才科技创新项目),2016.07-2019.07,10万元,201605D211026,在研,主持人。

3.昆虫几丁质酶5调控胚胎时期蜕皮的分子机理研究,中国博士后基金面上资助,2016.05-2018.05,5万元,在研,主持人。

4.c-Fos介导的巴西苏木素抑制膀胱癌T24细胞机理研究,山西省高校创新研究项目,2014.07-2016.12, 4万元,2014106,结题。

 

专利

1.一种飞蝗胚胎显微注射预处理装置;张婷婷;董卿,实用新型专利,201721494564.0,     山西大学

2.一种用于放置显微注射针的固定和消毒装置;张婷婷;张帅娜;实用新型专利,20160746165.8,山西大学

3.一种用于固定显微注射蝗虫卵的培养皿;张婷婷;柳伟伟;使用新型专利;20162074623.1,山西大学

 

代表性论文

1. Zhang T, Liu W#, Li D, Gao L, Ma E, Li S, Moussian B*, Zhang J*. LmCht5-1 is essential for the molting of the pro-nymph during embryonic development of Locusta migratoria. Insect biochemistry and molecular biology 2018.

2. Zhang T*, Liu W, Gao L, Li R, Fu S, Liu X, Li D, Liu W, Dong Q, Zhang J*. The Antibody Preparation and Expression Analysis of Chitinase 5-1 in Locusta migratoria. Scientia Agricultura Sinica 2018(12): 2418-2428.(Chinese)

3. Zhang T, He J#, Zhang S, Wang G, Ma E, Wang J, Yang X*, Zheng Y*, Zhang J*. Brazilin induces T24 cell death through c-Fos and GADD45β independently regulated genes and pathways.

4. Liu W, Li R, Fu S, Dong Q, Zhang M, Zhang X, Zhang J, Zhang T*. Observation of the development pattern and morphological change of serosal cuticle in Locusta migratoria (Orthoptera: Acrididae) with an optimized paraffin section method. Acta Entomologica Sinica 2018, 61(6): 733-740. (Chinese)

5. Zhang M, Zhao P, Yin J, Li T, Zhang T, Cao T, Ma E*. Characterization of the complete mitochondrial genome of Parnassius nomion (Lepidoptera: Parnassiidae) and analysis of the higher-level phylogenetic relationships of butterflies based on mitochondrial genome. Acta Entomologica Sinica 2017, 60(11): 1324-1338. (Chinese)

6. Zhan W, Wang W, Han T, Xie C, Zhang T, Gan M, Wang J*. COMMD9 promotes TFDP1/E2F1 transcriptional activity via interaction with TFDP1 in non-small cell lung cancer. Cellular signalling 2017, 30: 59-66.

7. Han T, Guo M, Zhang T, Gan M, Xie C, Wang J*. A novel glutaminase inhibitor-968 inhibits the migration and proliferation of non-small cell lung cancer cells by targeting EGFR/ERK signaling pathway. Oncotarget 2017, 8(17): 28063-28073.

8. Zhang X, Li Y, Wang J, Zhang T, Li T, Dong W, Ma E, Zhang J*. Identification and characteristic analysis of the catalase gene from Locusta migratoria. Pesticide biochemistry and physiology 2016, 132: 125-131.

9. Yan Q, Xu K, Xing J, Zhang T, Wang X, We Z, Ren C, Liu Z, Shao S, Zhang Z*. Multiplex CRISPR/Cas9-based genome engineering enhanced by Drosha-mediated sgRNA-shRNA structure. Scientific reports 2016, 6: 38970.

10. Xu K, Liu Z, Zhang L, Zhang T, Zhang Z*. SiRNA In Vivo-Targeted Delivery to Murine Dendritic Cells by Oral Administration of Recombinant Yeast. Methods in molecular biology (Clifton, NJ) 2016, 1364: 165-181.

11Liu Z, Zhou G, Ren C, Xu K, Yan Q, Li X, Zhang T, Zhang Z*. Oral administration of myostatin-specific recombinant Saccharomyces cerevisiae vaccine in rabbit. Vaccine 2016, 34(20): 2378-2382.

12. He J, Zhang T, Zhang S, Yang X, Ma E, Wang J, Zheng Y, Zhang J*. siRNA Screening of Target Gene for Brazilin Lethal to Bladder Cancer. Journal of Shanxi University (Natural Science Edition) 2016(4): 665-671. (Chinese)

13. Zhang T, Liu W, Li T, Zhang M, Zhang X, Ma E, Zhang J*. RNA-guided genome editing technology CRISPR/Cas9 and its application in insects. Journal of Tianjin Normal University ( Natural Science Edition ) 2015, 35(03): 61-65. (Chinese)

14. Zhang T, Fan X#, Song L, Ren L, Ma E, Zhang S, Ren L*, Zheng Y*, Zhang J*. c-Fos is involved in inhibition of human bladder carcinoma T24 cells by brazilin. IUBMB life 2015, 67(3): 175-181.

15. Zhang C, Xu K, Hu L, Wang L, Zhang T, Ren C, Zhang Z*. A suicidal zinc finger nuclease expression coupled with a surrogate reporter for efficient genome engineering. Biotechnology letters 2015, 37(2): 299-305.

16. Xu K#, Zhang T#, Guo L, Xin Y, Zhang L, Zhang Z*. Alternative methods for the efficient construction of short hairpin RNA expression vectors. Analytical biochemistry 2015, 478: 23-25.

17. Xu K, Ren C, Liu Z, Zhang T, Zhang T, Li D, Wang L, Yan Q, Guo L, Shen J, Zhang Z*. Efficient genome engineering in eukaryotes using Cas9 from Streptococcus thermophilus. Cellular and molecular life sciences : CMLS 2015, 72(2): 383-399.

18. Ren L, Song L, Zhang T, Ma E, Zheng Y, Ren L, Zhang J*. Construction and Expression of Eukaryotic Expression Vector HO-1 and its Roles in Bladder Cancer T24 Cells. Journal of Shanxi University (Natural Science Edition) 2015(1): 150-154. (Chinese)

19. Liu J, Zhang J, Li D, Zhang T, Ma E, Zhang J*. Bioinformatics and Tissue-Specific Expression Analysis of Carboxylesterase Genes from Oxya chinensis. Scientia Agricultura Sinica 2015, 48(21): 4272-4284. (Chinese)

20. Gao Ce, Ren X, Zhang X, Zhang T, Zhang J, Ma E, Wu H*. Prokaryotic expression of the CYP408B1 and CYP409A1 genes in Locusta migratoria. Chinese Journal of Applied Entomology 2015, 52(01): 153-161. (Chinese)

21. Zhang C, Wang L, Ren G, Li Z, Ren C, Zhang T, Xu K, Zhang Z*. Targeted disruption of the sheep MSTN gene by engineered zinc-finger nucleases. Molecular biology reports 2014, 41(1): 209-215.

22. Song L, Ren L, Zhang T, Ma E, Zheng Y, Ren L, Zhang J*. Overexpression of GADD45β Inhibited Proliferation of Bladder Cancer T24 Cells. Journal of Shanxi University (Natural Science Edition) 2014(4): 625-629. (Chinese)

 

联系方式
E-mail:zhangyanqiu3520@sxu.edu.cn

微信:A1236-pp

电话:I86-35I8-5746

 

 

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